RSIS Repository Open-access research from RSIS International journals

International Journal of Research and Scientific Innovation (IJRSI)

Concurrent Validation and Statistical Analysis of Novel Bi-Layer Floating Tablet of Sucralfate and Metoprolol Succinate

byDr. Sreedhar Ranjan Das; Dr Santosh Kumar Bala; Dr kalakar Bala; Somya Ranjan Sahoo

Published June 18, 2026  •  Vol. 13, Issue 6, pp. 400–405Open Access
DOI: 10.51244/IJRSI.2026.1306000023

Abstract

The research work is based on validation and statistical analysis of Bilayer Floating Tablet containing bilayer floating tablet of Sucralfate and Metoprolol Succinate. First the initially formulated and evaluated Bi layer floating tablet of Sucralfate and Metoprolol succinate (DSFMS). We performed the stability study as per the ICH guideline. Then evaluation of the tablets according to Concurrent validation process. Then final resultant value compared with the initial resultant values and checked the equivalency with the acceptance criteria of Bilayer Floating Tablet. Then statistical analysis were done by calculating mean deviation and standard aviation. Then compared statistical parameters a over limit or under limit.
After stability study and Concurrent validation of (DSFMS) it is confirmed that the formulation fulfill all the acceptance criteria of Bilayer floating tablet. It is confirmed that the formulation (DSFMS) satisfying all acceptance criteria of Bilayer floating tablet. The statistical parameters are under limit.

Keywords: Ulcer protective, Sucralfate, Antihypertensive, Metoprolol Succinate, Bilayer floating tablet

JournalInternational Journal of Research and Scientific Innovation (IJRSI)
ISSN2321-2705
Volume / IssueVolume 13, Issue 6
Pages400–405
Publication dateJune 18, 2026
DOI10.51244/IJRSI.2026.1306000023
PublisherRSIS International
LicenseOpen Access

How to cite this article

Dr. Sreedhar Ranjan Das, Dr Santosh Kumar Bala, Dr kalakar Bala, & Somya Ranjan Sahoo (2026). Concurrent Validation and Statistical Analysis of Novel Bi-Layer Floating Tablet of Sucralfate and Metoprolol Succinate. International Journal of Research and Scientific Innovation (IJRSI), 13(6), 400-405. https://doi.org/10.51244/IJRSI.2026.1306000023

BibTeX

@article{Dr2026,
  title   = {Concurrent Validation and Statistical Analysis of Novel Bi-Layer Floating Tablet of Sucralfate and Metoprolol Succinate},
  author  = {Dr. Sreedhar Ranjan Das and Dr Santosh Kumar Bala and Dr kalakar Bala and Somya Ranjan Sahoo},
  journal = {International Journal of Research and Scientific Innovation (IJRSI)},
  volume  = {13},
  number  = {6},
  pages   = {400--405},
  year    = {2026},
  doi     = {10.51244/IJRSI.2026.1306000023},
  publisher = {RSIS International}
}