Burden of Antipsychotic-induced Parkinsonism: A Case Report

Abstract

Background
A wide range of side effects have been reported since the discovery of antipsychotics, amongst which are the extrapyramidal side effects that occur as a result of excessive blockade of D2 receptors in the brain.
Parkinsonism resulting from use of antipsychotics or other psychotropic medications characteristically presents with rigidity, bradykinesia and tremors, and this has significantly added to the burden of illness in patients and worsened burden of care in caregivers.
Case presentation
We present the case of a 29year old man who was previously managed with first generation antipsychotics for a psychotic disorder at a peripheral centre but left on high dose of the medication after remission. He presented at our facility with severe features of drug-induced parkinsonism without symptoms of psychosis. He was managed on admission for four weeks and only became free of features of parkinsonism after six weeks of treatment with anticholinergic medication.
Conclusion
Asides from the burden of primary illness, antipsychotic-induced parkinsonism causes additional distress and impairment to patients as it was with the reported case. However, adequate anticipation and management of attendant EPSE is very crucial in reducing this additional morbidity and burden associated with managing patients with neuro-psychiatric disorders.