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International Journal of Research and Scientific Innovation (IJRSI)

Pharmacological Screening of Moringa Oleifera : In Vitro Anti-Inflammatory and Antimicrobial Activities

byMohan Eswar Raju Thotakura; Yasaswini Yedlapalli; Vinay Sai Vella; Dr. Dhabal Kumar Satapathy; Dr. Srinivasu Matta; Dr. Bhaskara Raju Vatchavai

Published May 19, 2026  •  Vol. 13, Issue 4, pp. 2848–2865Open Access
DOI: 10.51244/IJRSI.2026.1304000243

Abstract

In Ayurveda, the traditional medicinal plant Moringa Oleifera—also known as horse radish tree is highly regarded for its healing qualities. This study aims to evaluate moringa oleifera extracts' antibacterial and anti-inflammatory qualities in vitro. The anti-inflammatory potential was assessed using the membrane stabilizing and protein denaturation methods. The antibacterial effectiveness against particular strains of bacteria and fungus was examined using the agar well diffusion method. Initial phytochemical testing revealed the presence of flavonoids, alkaloids, phenolics, and terpenoids; these substances might be in charge of the biological activities found. The extracts demonstrated significant antioxidant activity in a dose-dependent manner. The organism's significant anti-inflammatory qualities supported its traditional use in treating inflammatory illnesses. Additionally, the extracts demonstrated strong antifungal and antibacterial activity towards common strains of fungus and both Gram-positive and Gram-negative bacteria. Since it is used to boost a woman's milk production and is occasionally recommended for anemia, it is referred to as "mother's best friend" in the Philippines. Examining the antibacterial and anti-inflammatory qualities of several Moringa oleifera leaf extracts in vitro was the aim of the present one study.

Keywords: Anti-bacterial, Anti-inflammatory, Phenolic compounds

JournalInternational Journal of Research and Scientific Innovation (IJRSI)
ISSN2321-2705
Volume / IssueVolume 13, Issue 4
Pages2848–2865
Publication dateMay 19, 2026
DOI10.51244/IJRSI.2026.1304000243
PublisherRSIS International
LicenseOpen Access

How to cite this article

Mohan Eswar Raju Thotakura, Yasaswini Yedlapalli, Vinay Sai Vella, Dr. Dhabal Kumar Satapathy, Dr. Srinivasu Matta, & Dr. Bhaskara Raju Vatchavai (2026). Pharmacological Screening of Moringa Oleifera : In Vitro Anti-Inflammatory and Antimicrobial Activities. International Journal of Research and Scientific Innovation (IJRSI), 13(4), 2848-2865. https://doi.org/10.51244/IJRSI.2026.1304000243

BibTeX

@article{Mohan2026,
  title   = {Pharmacological Screening of  Moringa Oleifera : In Vitro Anti-Inflammatory and Antimicrobial Activities},
  author  = {Mohan Eswar Raju Thotakura and Yasaswini Yedlapalli and Vinay Sai Vella and Dr. Dhabal Kumar Satapathy and Dr. Srinivasu Matta and Dr. Bhaskara Raju Vatchavai},
  journal = {International Journal of Research and Scientific Innovation (IJRSI)},
  volume  = {13},
  number  = {4},
  pages   = {2848--2865},
  year    = {2026},
  doi     = {10.51244/IJRSI.2026.1304000243},
  publisher = {RSIS International}
}