Pharmacological Screening of Moringa Oleifera : In Vitro Anti-Inflammatory and Antimicrobial Activities

by Dr. Bhaskara Raju Vatchavai, Dr. Dhabal Kumar Satapathy, Dr. Srinivasu Matta, Mohan Eswar Raju Thotakura, Vinay Sai Vella, Yasaswini Yedlapalli

Published: May 19, 2026 • DOI: 10.51244/IJRSI.2026.1304000243

Abstract

In Ayurveda, the traditional medicinal plant Moringa Oleifera—also known as horse radish tree is highly regarded for its healing qualities. This study aims to evaluate moringa oleifera extracts' antibacterial and anti-inflammatory qualities in vitro. The anti-inflammatory potential was assessed using the membrane stabilizing and protein denaturation methods. The antibacterial effectiveness against particular strains of bacteria and fungus was examined using the agar well diffusion method. Initial phytochemical testing revealed the presence of flavonoids, alkaloids, phenolics, and terpenoids; these substances might be in charge of the biological activities found. The extracts demonstrated significant antioxidant activity in a dose-dependent manner. The organism's significant anti-inflammatory qualities supported its traditional use in treating inflammatory illnesses. Additionally, the extracts demonstrated strong antifungal and antibacterial activity towards common strains of fungus and both Gram-positive and Gram-negative bacteria. Since it is used to boost a woman's milk production and is occasionally recommended for anemia, it is referred to as "mother's best friend" in the Philippines. Examining the antibacterial and anti-inflammatory qualities of several Moringa oleifera leaf extracts in vitro was the aim of the present one study.