“A Study on the Daignostic Role of Diffusion Weighted MRI in Acute Ishemic Stroke’’

Abstract

Introduction: Acute ischemic stroke is a leading cause of morbidity and mortality worldwide. Early diagnosis is critical for timely intervention, especially within the narrow therapeutic window. Non-contrast CT has limited sensitivity in early detection. Diffusion-weighted MRI (DWI) offers superior early diagnostic capability.
Aims and objectives: To evaluate the diagnostic accuracy and clinical role of diffusion-weighted MRI in detecting acute ischemic stroke.
Materials and methods: A prospective observational study was conducted on 50–100 patients presenting with clinical features of acute ischemic stroke. MRI, including DWI and ADC mapping, was performed within 24 hours of symptom onset, findings were compared with non-contrast CT where available.
Results: DWI MRI detected acute infarcts in the majority of cases, including those with normal CT findings. Hyperintense signals on DWI with corresponding hypointensity on ADC maps confirmed restricted diffusion. The middle cerebral artery (MCA) territory was most commonly involved (42%). DWI showed significantly higher sensitivity (96%) compared to CT (28%).
Conclusion: DWI MRI is a highly sensitive and reliable imaging modality for early detection of acute ischemic stroke and should be routinely used when available.