Spectroscopic and Biological Studies of Cr (III), Co (III) And Zn (II) Metal Ion Complexes Derived from 2-Phenyl-4H-Benzo[D] [3,1]-Oxazin-4-One Ligand

Abstract

The preparation of Novel heterocyclic ligand PHBO (2-Phenyl-4H-benzo[d][3,1]-oxazin-4-one) is synthesized from the condensation of anthranilic acid, benzoyl chloride and acetic anhydride. The heterocyclic classes which have drawn attention towards its synthesis because of their innumerable biological activities like antibacterial, antifungal, antiviral, antitumor and anticancer activities. A new PHBO complexes derived from 2-Phenyl-4H-benzo[d] [3,1]-oxazin-4-one with Cr (III), Zn (II) ions. The metal chelates were synthesized and characterized by IR, NMR, TGA-DTA, XRD, Elemental analysis and molar conductance measurements. The PHBO ligand and their metal chelates have been tested for their antimicrobial activity and anticancer activity.