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International Journal of Research and Scientific Innovation (IJRSI)

Spectral and Microscopic Investigation of Betamethasone/ Cyclodextrin Covered Ag/Co/ Nanorods

byAyyadurai Mani; Narayanasamy Rajendiran; Poomalai Senthilraja; S. Senthilmurugan

Published April 21, 2026  •  Vol. 13, Issue 3, pp. 2731–2743Open Access
DOI: 10.51244/IJRSI.2026.1303000237

Abstract

Silver/cobalt/betamethasone/cyclodextrin nanoparticles are synthesized and characterized by UV-visible, fluorescence, FE-SEM, TEM, differential scanning colorimeter, FTIR, and XRD methods. Single emission was observed in α-CD and β-CD. Compared to the BEM/CD inclusion complex, a red or blue shifted absorption and fluorescence maximum was seen in Ag/BEM/β-CD and Ag/Co/BEM/β-CD nanoparticles. Nanoparticle size was measured by TEM-EDS and XRD methods. TEM images showed nanorods are formed in Ag/BEM/β-CD and Ag/Co/BEM/β-CD. Antibacterial activity results revealed that the Ag/BEM/β-CD and Ag/Co/BEM/β-CD nanomaterials show more antibacterial activity than isolated BEM drug. Further, BEM exhibits anticancer activity against the 2oh4 protein.

Keywords: Betamethasone, Cyclodextrin, Inclusion complex, Silver nano, Nanorod,

JournalInternational Journal of Research and Scientific Innovation (IJRSI)
ISSN2321-2705
Volume / IssueVolume 13, Issue 3
Pages2731–2743
Publication dateApril 21, 2026
DOI10.51244/IJRSI.2026.1303000237
PublisherRSIS International
LicenseOpen Access

How to cite this article

Ayyadurai Mani, Narayanasamy Rajendiran, Poomalai Senthilraja, & S. Senthilmurugan (2026). Spectral and Microscopic Investigation of Betamethasone/ Cyclodextrin Covered Ag/Co/ Nanorods. International Journal of Research and Scientific Innovation (IJRSI), 13(3), 2731-2743. https://doi.org/10.51244/IJRSI.2026.1303000237

BibTeX

@article{Ayyadurai2026,
  title   = {Spectral and Microscopic Investigation of Betamethasone/ Cyclodextrin Covered Ag/Co/ Nanorods},
  author  = {Ayyadurai Mani and Narayanasamy Rajendiran and Poomalai Senthilraja and S. Senthilmurugan},
  journal = {International Journal of Research and Scientific Innovation (IJRSI)},
  volume  = {13},
  number  = {3},
  pages   = {2731--2743},
  year    = {2026},
  doi     = {10.51244/IJRSI.2026.1303000237},
  publisher = {RSIS International}
}