Comprehensive Review on Analytical Method Development and Validation of Rosuvastatin Calcium
by Dr. Uday A. Deokate, Lalit Bhoye, Muskan Mulla, Pratiksha Kamble, Vaishnavi Punase
Published: April 25, 2026 • DOI: 10.51244/IJRSI.2026.1303000239
Abstract
Rosuvastatin Calcium is a potent antihyperlipidemic drug belonging to the class of HMG-CoA reductase inhibitors i.e statins. It acts by selectively inhibiting the enzyme 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase, which is responsible for cholesterol synthesis which helps in increasing LDL clearance from blood. The present review focuses on the different Analytical Method Development of Rosuvastatin and QbD based approaches.