International Journal of Research and Scientific Innovation (IJRSI)
Pharmacological Evaluation of Imperata Cylindrica Crude Extract as Anti-Angiogenic Potential: Network Pharmacology, Molecular Docking Prediction with ADMET Analysis and CAM Assay Visualization
Published February 28, 2026 • Vol. 13, Issue 2, pp. 616–648Open Access
DOI: 10.51244/IJRSI.2026.13020055
Abstract
This study investigated the anti-angiogenic potential of Imperata cylindrica (cogon grass) leaf extract through an integrated network pharmacology–guided in silico approach coupled with in vivo validation, focusing on the multi-target behavior of its bioactive compounds. Given the central role of angiogenesis in tumor growth and metastasis, identifying plant-derived compounds capable of modulating angiogenic pathways remains a strategic priority in cancer research.
Keywords: Imperata cylindrica, angiogenesis, bioactive compounds
| Journal | International Journal of Research and Scientific Innovation (IJRSI) |
|---|---|
| ISSN | 2321-2705 |
| Volume / Issue | Volume 13, Issue 2 |
| Pages | 616–648 |
| Publication date | February 28, 2026 |
| DOI | 10.51244/IJRSI.2026.13020055 |
| Publisher | RSIS International |
| License | Open Access |
How to cite this article
Sheemaiah Kylle L. Hasim, Mary Chris M. Castillo, Riza Jane T. Andig, Julio Raymundo M. Pasagui, & Judie L. Velasco (2026). Pharmacological Evaluation of Imperata Cylindrica Crude Extract as Anti-Angiogenic Potential: Network Pharmacology, Molecular Docking Prediction with ADMET Analysis and CAM Assay Visualization. International Journal of Research and Scientific Innovation (IJRSI), 13(2), 616-648. https://doi.org/10.51244/IJRSI.2026.13020055
BibTeX
@article{Sheemaiah2026,
title = {Pharmacological Evaluation of Imperata Cylindrica Crude Extract as Anti-Angiogenic Potential: Network Pharmacology, Molecular Docking Prediction with ADMET Analysis and CAM Assay Visualization},
author = {Sheemaiah Kylle L. Hasim and Mary Chris M. Castillo and Riza Jane T. Andig and Julio Raymundo M. Pasagui and Judie L. Velasco},
journal = {International Journal of Research and Scientific Innovation (IJRSI)},
volume = {13},
number = {2},
pages = {616--648},
year = {2026},
doi = {10.51244/IJRSI.2026.13020055},
publisher = {RSIS International}
}