Pharmacological Evaluation of Imperata Cylindrica Crude Extract as Anti-Angiogenic Potential: Network Pharmacology, Molecular Docking Prediction with ADMET Analysis and CAM Assay Visualization
by Judie L. Velasco, Julio Raymundo M. Pasagui, Mary Chris M. Castillo, Riza Jane T. Andig, Sheemaiah Kylle L. Hasim
Published: February 28, 2026 • DOI: 10.51244/IJRSI.2026.13020055
Abstract
This study investigated the anti-angiogenic potential of Imperata cylindrica (cogon grass) leaf extract through an integrated network pharmacology–guided in silico approach coupled with in vivo validation, focusing on the multi-target behavior of its bioactive compounds. Given the central role of angiogenesis in tumor growth and metastasis, identifying plant-derived compounds capable of modulating angiogenic pathways remains a strategic priority in cancer research.