The Science of Sustained-Release Medications

Abstract

Sustained release pharmaceutical products became a very useful tool in medical practice, actual and perceived advantages to the patients. Sustained release is also providing promising way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body. Sustained release system are considered a wiser approach for the drug with short half lives and which requires repeated dosing, they are easy to formulate and irrespective of absorption process from gastrointestinal tract after oral administration. Sustained systems include any drug delivery system that achieves slow release of drug over an extended period of time. Now a days as very few drugs are coming out of research and development and already existing drugs are suffering the problem of resistance due to their irritational use specifically in case of drug like antibiotics. The basic rationale of sustained release drug delivery system optimizes of the biopharmaceutical and pharmacokinetic and pharmacodynamics properties of the drug in such a way that utility is maximized, side effect reduced and cure of the disease is achieved. The principle goal of sustained release form is the improvements of drug therapy assessed by the relationship between advantages of the use of sustained release system. This article contains the basic information regarding sustained release formulation and also the different types of the same.