Efficacy of Mustadi Yapan Basti in Geriatric Care: a Randomized Controlled Trial

Abstract

Background: Vruddhavastha (geriatric age, 60-100 years) is characterized by Vata dosha predominance, tissue depletion, and diminished strength. Mustadi Yapan Basti, a classical Ayurvedic formulation, is traditionally indicated for strength promotion and rejuvenation.
Objective: To evaluate the efficacy and safety of Mustadi Yapan Basti compared with Madhutailik Yapan Basti in managing geriatric symptoms.
Methods: Sixty-two patients (60-100 years) were randomized to receive either Mustadi Yapan Basti (Group A, n=31) or Madhutailik Yapan Basti (Group B, n=31) daily for 8 days, with follow-up on Day 24. Primary outcomes included strength (Bala), energy (Utsaha), breathlessness (Ayasen Shwas), and Vata symptoms. Secondary outcomes included walking time and laboratory parameters.
Results: Group A demonstrated superior improvements: Bala (96.30% vs 53.24%, p<0.01), Utsaha
(90.85% vs 51.03%, p<0.01), Ayasen Shwas (64.35% vs 41.10%, p<0.05), Vata symptoms (68.10% vs
42.55%, p<0.01), and walking time (31.79% vs 18.38%, p<0.01). Marked improvement (≥66% relief) occurred in 74.19% of Group A versus 29.03% of Group B. Significant improvements in hemoglobin (+4.24%), ESR (22.18%), and serum calcium (+6.98%) were observed in Group A. Adverse events were minimal and selflimiting (Group A: 16.13%; Group B: 38.71%).
Conclusion: Mustadi Yapan Basti is highly effective and safe for managing geriatric symptoms, demonstrating superior efficacy with sustained benefits and excellent tolerability.