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International Journal of Research and Innovation in Applied Science (IJRIAS)

Formulation and Evaluation of Olopatadine Hydrochloride Opthalmic Solution

byAkansha Athiya; Deepak koshti; Ramdarshan Parashar; VaibhavRajoriya; YogeshSharma; Ajay Singh Thakur

Published July 18, 2026  •  Vol. 11, Issue 6, pp. 3839–3859Open Access
DOI: 10.51584/IJRIAS.2026.11060285

Abstract

Olopatadine Hydrochloride is a selective histamine H1-receptor antagonist and mast cell stabilizer widely used in the treatment of allergic conjunctivitis. The present study aimed to formulate and evaluate a sterile ophthalmic solution of Olopatadine Hydrochloride with enhanced stability, safety, and patient compliance. The ophthalmic solution was prepared using suitable excipients, including buffering agents, tonicity adjusters, preservatives, and viscosity enhancers to achieve optimal physicochemical properties and ocular compatibility.

Keywords: Olopatadine Hydrochloride, Ophthalmic Solution, Allergic Conjunctivitis, Sterility

JournalInternational Journal of Research and Innovation in Applied Science (IJRIAS)
ISSN2454-6194
Volume / IssueVolume 11, Issue 6
Pages3839–3859
Publication dateJuly 18, 2026
DOI10.51584/IJRIAS.2026.11060285
PublisherRSIS International
LicenseOpen Access

How to cite this article

Akansha Athiya, Deepak koshti, Ramdarshan Parashar, VaibhavRajoriya, YogeshSharma, & Ajay Singh Thakur (2026). Formulation and Evaluation of Olopatadine Hydrochloride Opthalmic Solution. International Journal of Research and Innovation in Applied Science (IJRIAS), 11(6), 3839-3859. https://doi.org/10.51584/IJRIAS.2026.11060285

BibTeX

@article{Akansha2026,
  title   = {Formulation and Evaluation of Olopatadine Hydrochloride Opthalmic Solution},
  author  = {Akansha Athiya and Deepak koshti and Ramdarshan Parashar and VaibhavRajoriya and YogeshSharma and Ajay Singh Thakur},
  journal = {International Journal of Research and Innovation in Applied Science (IJRIAS)},
  volume  = {11},
  number  = {6},
  pages   = {3839--3859},
  year    = {2026},
  doi     = {10.51584/IJRIAS.2026.11060285},
  publisher = {RSIS International}
}