International Journal of Research and Innovation in Applied Science (IJRIAS)
Synthesis and Characterization of Antibacterial Agents: Spectroscopic Insights and Biological activity Evaluation
Published March 17, 2026 • Vol. 11, Issue 2, pp. 1239–1243Open Access
DOI: 10.51584/IJRIAS.2026.110200111
Abstract
Antibacterial resistance continues to threaten public health worldwide, prompting the development of novel small-molecule antibacterial agents. Herein, we report the synthesis, spectroscopic characterization, and antibacterial activity assessment of a series of novel heterocyclic derivatives. Structural confirmation was achieved through FT-IR, 1H / 13C NMR, and mass spectrometry. Antibacterial efficacy was evaluated against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) strains. The synthesized compounds exhibited comparable or superior efficacy relative to standard antibiotics, supporting their potential as future therapeutic agents.
Keywords: Antibacterial, Preparation, potential, Heterocyclic, Spectra
| Journal | International Journal of Research and Innovation in Applied Science (IJRIAS) |
|---|---|
| ISSN | 2454-6194 |
| Volume / Issue | Volume 11, Issue 2 |
| Pages | 1239–1243 |
| Publication date | March 17, 2026 |
| DOI | 10.51584/IJRIAS.2026.110200111 |
| Publisher | RSIS International |
| License | Open Access |
How to cite this article
Gopala Krishna Murthy H.R (2026). Synthesis and Characterization of Antibacterial Agents: Spectroscopic Insights and Biological activity Evaluation. International Journal of Research and Innovation in Applied Science (IJRIAS), 11(2), 1239-1243. https://doi.org/10.51584/IJRIAS.2026.110200111
BibTeX
@article{Gopala2026,
title = {Synthesis and Characterization of Antibacterial Agents: Spectroscopic Insights and Biological activity Evaluation},
author = {Gopala Krishna Murthy H.R},
journal = {International Journal of Research and Innovation in Applied Science (IJRIAS)},
volume = {11},
number = {2},
pages = {1239--1243},
year = {2026},
doi = {10.51584/IJRIAS.2026.110200111},
publisher = {RSIS International}
}