Effects of Essential Oils in Swiss Albino Mice

Abstract

The present study was untaken to use essential oils in Swiss albino mice in the department of Pathobiology. Essential oils (Eos) are concentrated liquids of complex mixtures of volatile compounds. Essential oils are a good source of several bioactive compounds, which have antioxidative and antimicrobial properties. The experiment was carried out on Swiss Albino mice (Mus musculus). Twenty-Five (25) mice of 7 days old were bought from the Animal Resource Center, ICDDR, B. The collected mice had neither any developmental disorders, detectable genital diseases nor other diseases that may cause any problem in the experiment or affect the result of the experiment. Twenty-five (25) mice at 21 days old were randomly used for the experiment and the mice were divided into five groups and each group will consists of five mice. Groups I, II, III & IV received orally Pulmo Gold 1ml/5L water, Activo Powder -100mg/kg feed, Reference liquid-5ml/1L water and Respocare liquid-5ml/1L doses of the essential oils, respectively. Group-V (control group) will be supplied with normal foods and ad libitum water. In case of control group (group-V), the body weight gaining rate is lower than the other treated groups. The highest number of microorganisms are found in control group and 4 samples are contaminated with microbes out of 5 samples incased of kidneys and intestine. On the other hands 5 samples are contaminated incased of liver. The lowest number of organisms are found in group II (Activo Powder) and 1 sample of kidney, liver and intestine are associated with microorganisms.