International Journal of Research and Innovation in Applied Science (IJRIAS)
Synthesis and Microbial Activities of 2, 5, 6-Substituted Benzimidazole Derivatives
Published December 9, 2025 • Vol. 10, Issue 11, pp. 392–398Open Access
DOI: 10.51584/IJRIAS.2025.101100038
Abstract
Benzimidazole derivatives are the analogues of purine nucleosides which are found in human body. These are an important heterocyclic organic compounds containing phenyl ring (six membered ring) fused with imidazole (five membered ring) which possesses wide range of starting material for various compounds and exhibit clinical applications such as anti-inflammatory, antibacterial, antifungal, antiviral, analgesic, proton pump inhibitors, antihistamines, anticancer, etc. The presence of electron-donating groups (OH, -CH3, -OCH3) causes significant increase in the biological activity, while the electron-withdrawing groups (-Cl, -Br,–NO2) decreases the biological activity of synthesized of benzimidazole derivatives.
Keywords: Benzimidazole; 4,5-substituted phenylene-1,2-diamine
| Journal | International Journal of Research and Innovation in Applied Science (IJRIAS) |
|---|---|
| ISSN | 2454-6194 |
| Volume / Issue | Volume 10, Issue 11 |
| Pages | 392–398 |
| Publication date | December 9, 2025 |
| DOI | 10.51584/IJRIAS.2025.101100038 |
| Publisher | RSIS International |
| License | Open Access |
How to cite this article
Dhondiba Vishwanath, Devaraju, & Vijayanand Vithalrao (2025). Synthesis and Microbial Activities of 2, 5, 6-Substituted Benzimidazole Derivatives. International Journal of Research and Innovation in Applied Science (IJRIAS), 10(11), 392-398. https://doi.org/10.51584/IJRIAS.2025.101100038
BibTeX
@article{Dhondiba2025,
title = {Synthesis and Microbial Activities of 2, 5, 6-Substituted Benzimidazole Derivatives},
author = {Dhondiba Vishwanath and Devaraju and Vijayanand Vithalrao},
journal = {International Journal of Research and Innovation in Applied Science (IJRIAS)},
volume = {10},
number = {11},
pages = {392--398},
year = {2025},
doi = {10.51584/IJRIAS.2025.101100038},
publisher = {RSIS International}
}